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	<title>China Bio Law &#187; international competition</title>
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		<title>Six Perspectives on Chinese Science</title>
		<link>http://www.chinabiolaw.com/2010/01/six-perspectives-on-chinese-science/</link>
		<comments>http://www.chinabiolaw.com/2010/01/six-perspectives-on-chinese-science/#comments</comments>
		<pubDate>Sun, 24 Jan 2010 22:24:00 +0000</pubDate>
		<dc:creator>andrei</dc:creator>
				<category><![CDATA[international competition]]></category>
		<category><![CDATA[New York Times]]></category>
		<category><![CDATA[science]]></category>

		<guid isPermaLink="false">http://www.chinabiolaw.com/?p=18</guid>
		<description><![CDATA[On the 18th the NYT published one of its mini-debates, this time on the subject &#8220;Will China Achieve Science Supremacy?&#8221; The content is right up my alley and of interest to this blog, so I&#8217;ll run through the arguments of the six contributors. Gordon G. Chang wrote, &#8220;Hard Sciences Require &#160;Freedom, Too.&#8221; &#160;He asserts that [...]]]></description>
			<content:encoded><![CDATA[<p>On the 18th the NYT published one of its mini-debates, this time on the subject &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science">Will China Achieve Science Supremacy?</a>&#8221; The content is right up my alley and of interest to this blog, so I&#8217;ll run through the arguments of the six contributors.</p>
<p>Gordon G. Chang wrote, &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science#gordon"><b>Hard Sciences Require &nbsp;Freedom, Too</b></a><b>.</b>&#8221; &nbsp;He asserts that China&#8217;s one-party state has already smothered creativity in the &#8220;soft sciences&#8221; (polisci, history, economics, etc.), and that its current policies will do exactly the same in the &#8220;hard sciences.&#8221; &nbsp;He boils his argument down into the four following creativity-killers: &nbsp;the Communist Party&#8217;s orthodoxy, Marxist instruction in schools, a flawed educational system, and internet censorship.</p>
<p>I just can&#8217;t say I am all that convinced. &nbsp;While I certainly am no fan of the CCP&#8217;s policies in these areas, they simply don&#8217;t strike me as effectively precluding technological innovation. </p>
<p>As an example of how the CCP&#8217;s orthodoxy stifles genuine scientific advancement he describes the CCP&#8217;s policies re: China&#8217;s various minorities as an impediment to researchers who want to study the biological aspects of China&#8217;s ethnic or racial origins. &nbsp;This has a kernel truth, but Chang also claims that &#8220;wide swaths&#8221; of biology become sensitive areas because of such policies. &nbsp;While I agree that political considerations could potentially interfere with legitimate scientific inquiry, I strongly disagree with his assessment of the extent to which such control occurs. &nbsp;Would such &#8220;selective blindness&#8221; in a scientific community affect certain trends in scientific research? &nbsp;Yes. &nbsp;Would such &#8220;selective blindness&#8221; impede innovation across the board? &nbsp;I&#8217;m not so sure. &nbsp;Science is a lot larger than Chang gives it credit for.</p>
<p>As for the Marxist instruction in schools, he claims such ideological indoctrination results in &#8220;distraction from real research and study&#8221; and &#8220;stifles free thinking across the board.&#8221; &nbsp;Now perhaps I&#8217;m wearing rose-colored glasses here, but I think he greatly exaggerates the extent to which the scientific population is affected by required Marxist-Leninist classes. &nbsp;This might simply be anecdotal, but the vast majority of my Chinese friends and acquaintances who went through the university system thought these classes were ridiculous, boring, and a waste of time (after class, of course, they hop onto their computer, download Prison Break, Desperate Housewives, and 24 and distract themselves from &#8220;real research and study&#8221;). &nbsp;And while I don&#8217;t doubt that a percentage of the Chinese population may be negatively affected by such classes, but I do doubt that those who are so easily swayed would make for very good scientists in the first place. &nbsp;I mean, how often do you hear people claim that the U.S. will never be a scientifically innovative country because of the high prevalence of childhood religious instruction, yet another form of ideological indoctrination? &nbsp;I mean, at least Marxism-Leninism holds science and technology in high esteem.</p>
<p>The last points he makes are better, although not perfect. &nbsp;China&#8217;s educational and scientific environment does have serious shortcomings, and Chinese scientists have been vocal advocates of reform. &nbsp;They are keenly aware of how damaging incidences and allegations of academic or scientific misconduct are to China&#8217;s place in the international scientific community. &nbsp;As for his internet freedom argument, while I am persuaded by arguments that this will hurt innovation in China&#8217;s IT sector, I am less convinced that censorship or internet policy will be as serious an impediment in other areas of science. &nbsp;I&#8217;ve never seen Falungong on the front page of <a href="http://www.nature.com/nature/index.html">Nature</a> or <a href="http://www.sciencemag.org/">Science</a>, and most scientific topics are of neutral-importance to the CCP. &nbsp;Short of completely cutting off access to international sites, &nbsp;I don&#8217;t think there would be a serious impediment to potential innovation.</p>
<p>The next essay, &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science#cong"><b>A Climate for Misconduct</b></a>,&#8221; by Cong Cao, is the standard &#8220;what&#8217;s wrong with the Chinese scientific establishment&#8221; article. &nbsp;He highlights a number of issues. &nbsp;First, he discusses how the financial and political advantages attached to greater academic credentials can leads to scientists seizing risky or unethical opportunities to get to the top. &nbsp;I&#8217;ve always thought this was an interesting point, because it either means that giving scientists too much money equals bad science or counterproductive consequences, or simply that &nbsp;the methods used to vet legitimate advancement are lacking. &nbsp;Regarding the former, this <a href="http://blog.ted.com/2009/07/dan_pink_at_ted.php">TED talk</a>&nbsp;is good food for thought, because it claims that psychological experiments have consistently shown that financial incentives for creative work actually reduce productivity. &nbsp;Perhaps the fact that our scientists aren&#8217;t remunerated as well as athletes or movie stars is actually a pillar of American innovation…It is probably not far from the truth to claim that &nbsp;many scientists wouldn&#8217;t do what they do were it not for their love of what they do.</p>
<p>Following that argument, there&#8217;s the oft-repeated &#8220;too much emphasis on quantity&#8221; of publications and the &#8220;crushing institutional pressure&#8221; placed on scientists by the government. &nbsp;Cong Cao also alleges that it is nearly impossible to expose wrongful conduct among high-profile scientists, that the institutional processes that are responsible for monitoring scientific misconduct are not implemented properly (I&#8217;d like to know if he&#8217;s referring to specific institutions/regulations or if he&#8217;s speaking generally here), and that there is at least a correlative link between instances of scientific misconduct and the circumstances of China&#8217;s heavily commercialized society and corruption-heavy bureaucracy.</p>
<p>John Kao, in &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science#john"><b>Can Quantity Lead to Quality</b></a>,&#8221; acknowledges that China can have all the patents and publications in the world, but for it to truly have &#8220;innovative science&#8221; it will need to actively link its scientific and technological abilities to &#8220;entrepreneurship, design and social innovation.&#8221;</p>
<p>Vivek Wadhwa, in &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science#vivek"><b>Many Reasons to Return</b></a>,&#8221; presents some great statistics on how Chinese nationals who trained abroad and have been enticed to return to China &nbsp;have fared. &nbsp;Short answer&#8211;very, very well. &nbsp;Great conclusion:<br />
<blockquote>The bottom line is that the U.S. is providing China a huge amount of foreign aid without even realizing it. We’re exporting engines of economic growth and helping them become our long-term competitors.</p></blockquote>
<p>Jonathan Moreno&#8217;s &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science#jonathan"><b>The Stem Stell Example</b></a>&#8221; focuses a little bit more on what the United States should do to improve its scientific prowess. &nbsp;He basically says that 1) we should take advantage of our open society, which he believes translates into an ability to foster scientific exchange through personal relationships. &nbsp;I&#8217;m not really sure what he&#8217;s getting at in that sentence, but he goes on to say that a better visa system would help, so I&#8217;m assuming that by &#8220;scientific exchange through personal relationships&#8221; he means bringing in top<br />
-flight foreign nationals to do science here in the States. &nbsp;Then 2) we should also &#8220;invest in our patent system to ensure timely and valid awards.&#8221; &nbsp;This is a great sound bite but I have no idea what this means. &nbsp;Patent reform? &nbsp;More money to the USPTO? &nbsp;What? &nbsp;If I had to guess I&#8217;d say that he probably wants to make sure that the way our patent system functions works to foster and not stifle innovation. &nbsp;Easier said than done.</p>
<p>One odd thing he claims, which I haven&#8217;t heard of before, is that on a recent visit to China he was unable to access websites about U.S. research standards, among other innocuous topics. &nbsp;I would definitely like to know what search terms he was using and what websites he tried to visit before I believe this claim. &nbsp;In all my time spent lurking on the Sinophile blogosphere, I&#8217;ve never heard anything like that. </p>
<p>The final essay, &#8220;<a href="http://roomfordebate.blogs.nytimes.com/2010/01/18/will-china-achieve-science-supremacy/?ref=science#gang"><b>Strengths From the Top</b></a>&#8221; by Gang Xiao, deals with the factors that will make China&#8217;s &#8220;Thousand-Person Plan&#8221; successful. &nbsp;This refers to the government&#8217;s plan to recruit Chinese scientists and engineers back from abroad using fantastic incentives. &nbsp;He calls out the main stumbling blocks affecting the returnees: having to deal with the close-knit hierarchy of existing research networks, circumstances in which subjective factors often trump objective evaluation of science, and the lag-time involved in attempting to get resources from local governments and institutions. &nbsp;He presents the triumvirate of innovative science, the ability to &#8220;think independently, form collaboration networks without interference, and distribute and access information freely.&#8221; &nbsp;One final note, he comes out with this funky sentence, &#8220;China has the ability to achieve its goals because it has often done so once it determines that these objectives are imperative to its future.&#8221; &nbsp;Talk about tautology.</p>
<p>Most of these people also have China/Science books out, which has added almost 2000 pages to my &#8220;to-read-eventually&#8221; list&#8230;</p>
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		<title>Profile in Chinese Stem Cell Research</title>
		<link>http://www.chinabiolaw.com/2010/01/profile-in-chinese-stem-cell-research/</link>
		<comments>http://www.chinabiolaw.com/2010/01/profile-in-chinese-stem-cell-research/#comments</comments>
		<pubDate>Tue, 12 Jan 2010 17:03:00 +0000</pubDate>
		<dc:creator>andrei</dc:creator>
				<category><![CDATA[disease profile]]></category>
		<category><![CDATA[international competition]]></category>
		<category><![CDATA[stem cells]]></category>

		<guid isPermaLink="false">http://www.chinabiolaw.com/?p=16</guid>
		<description><![CDATA[This profile entry will be periodically updated as I come across more information. Posts Related to this profile follow. On China&#8217;s international competitiveness in the stem cell science: Regenerative Medicine Report (2010): reviewing article entitled &#8220;Cultivating regenerative medicine innovation in China.&#8221; New England Journal of Medicine&#160;Summary (2006): reviewing article entitled &#8220;Bit Player or Powerhouse? China [...]]]></description>
			<content:encoded><![CDATA[<p>This profile entry will be periodically updated as I come across more information.</p>
<p>Posts Related to this profile follow.</p>
<p>On China&#8217;s international competitiveness in the stem cell science:
<ul>
<li><a href="http://www.chinabiolaw.com/2010/01/i-think-i-was-trying-to-suggest.html">Regenerative Medicine Report</a> (2010): reviewing article entitled &#8220;Cultivating regenerative medicine innovation in China.&#8221;</li>
<li><a href="http://www.chinabiolaw.com/2010/01/china-and-stem-cell-research-just-not.html">New England Journal of Medicine&nbsp;Summary</a> (2006): reviewing article entitled &#8220;Bit Player or Powerhouse? China and Stem-Cell Research.&#8221;</li>
</ul>
<p>On <i>Reported</i> Chinese Stem Cell Breakthroughs (not verified):
<ul>
<li><a href="http://www.chinabiolaw.com/2009/12/norweigian-in-beijing-successful-brain.html">Cellonis Biotechnologies</a>&nbsp;(Beijing) &amp;&nbsp;<a href="http://www.chinabiolaw.com/2009/12/norwegian-in-beijing-part-ii-treatment.html">Glioma</a>&nbsp;(2009).</li>
<li>Nanshan People&#8217;s Hospital (Shenzhen) &amp; <a href="http://www.chinabiolaw.com/2010/01/i-think-i-was-trying-to-suggest.html">Spinal Cord Injury</a> (2006)</li>
</ul>
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		<title>China and Stem Cell Research: Just Not There Yet?</title>
		<link>http://www.chinabiolaw.com/2010/01/china-and-stem-cell-research-just-not/</link>
		<comments>http://www.chinabiolaw.com/2010/01/china-and-stem-cell-research-just-not/#comments</comments>
		<pubDate>Tue, 12 Jan 2010 16:52:00 +0000</pubDate>
		<dc:creator>andrei</dc:creator>
				<category><![CDATA[international competition]]></category>
		<category><![CDATA[pros and cons]]></category>
		<category><![CDATA[stem cells]]></category>

		<guid isPermaLink="false">http://www.chinabiolaw.com/?p=15</guid>
		<description><![CDATA[Just doing some general research on the progress of stem cell research in China. Here&#8217;s an old 2006 editorial in the New England Journal of Medicine, entitled &#8220;Bit Player or Powerhouse? China and Stem-Cell Research.&#8221; The editorial essentially declares that China has the potential to become a stem cell powerhouse, but it simply isn&#8217;t there [...]]]></description>
			<content:encoded><![CDATA[<p>Just doing some general research on the progress of stem cell research in China.</p>
<p>Here&#8217;s an old 2006 <a href="http://content.nejm.org/cgi/content/full/355/12/1191">editorial</a> in the New England Journal of Medicine, entitled &#8220;Bit Player or Powerhouse? China and Stem-Cell Research.&#8221;</p>
<p>The editorial essentially declares that China has the potential to become a stem cell powerhouse, but it simply isn&#8217;t there yet. &nbsp;China is accumulating stem cell expertise, but as of yet it does not have the scientific infrastructure required for creating an environment conducive to making scientific breakthroughs in the field. </p>
<p>What are the main problems?
<ol>
<li><b>Funding</b>. &nbsp;They emphasized that funding of stem cell science by the government is in fact extremely limited, despite all the press. &nbsp;The editorial says that the Ministry of Science and Technology funds stem cell research through two projects (basic and applied research programs), and provided ~$12 million USD to each between 2000 and 2005. &nbsp;Including local government expenses, the whole figure for government funded stem cell research in China, is only ~$38 million between 2000 and 2006. &nbsp;The editorial also claims that private sources of funding are &#8220;distinctly immature&#8221; in China.</li>
<li><b>Small talent pool</b>. &nbsp;It also gives a <a href="http://content.nejm.org/cgi/content/full/355/12/1191">list</a> of several leading stem cell researchers in China, I might look each of those up later, and says that there are between 300 and 400 Ph.D.s working on stem cells and seven &#8220;top-notch&#8221; labs associated with stem cells. &nbsp;The article takes note that the pool of lower level researchers is smaller, and promising students often go abroad for advanced training. &nbsp; And while China generally loses its students-cum-scientists to the United States, <a href="http://www.nytimes.com/2010/01/07/world/asia/07scholar.html">this trend may already be reversing</a>.</li>
<li><b>Limited collaboration</b>. &nbsp;The article faults Chinese scientists for being too intensely competitive in getting their worked recognized at the international level, rather than creating informal networks of domestic cooperation. &nbsp;This latter point about informal cooperative networks is one that I haven&#8217;t come across before, as most critiques of the Chinese scientific infrastructure focus on rigidity in the scientific hierarchy or the hyper-excessive focus on publication numbers.</li>
</ol>
<p>But then China has some aces up its sleeves:</p>
<ol>
<li><b>Cost advantage</b>. &nbsp;The editorial predicts that China should be able to maintain a cost advantage by being able to cheaply produced standardized components required for stem cell research, like laboratory animals and equipment for stem-cell manipulation. &nbsp;It is also conceivable that wages could remain depressed for lower level research workers and supporting staff. &nbsp;However, while the article admits that wages and material costs will rise as China develops, it also claims that more sophisticated sectors will retain a cost advantage for some time. &nbsp;I&#8217;d be interested in studying why this is.</li>
<li><b>Attitude towards embryos</b>. &nbsp;Here the editorial seems to conflate stem cell research, generally, with the moral disputes that occur over using human embryos in stem cell research. &nbsp;I wonder how many of those labs are actually doing stem cell research involving human embryonic stem cells. &nbsp;<a href="http://www.youtube.com/watch?v=vhyGlGgXMxY">Having said that</a>, the points it brings up are true. &nbsp;A very small part of the Chinese populace gets as aggravated about the use of human embryos in research as many portions of Western civil society. &nbsp;The most salient government restrictions involving experimentation with embryos are concerned with implantation of an experimented upon embryo rather than what happens to the embryo itself. &nbsp;All in all, the article is probably correct that there won&#8217;t be much &#8220;moral politicking&#8221; about the issue.</li>
<li><b>&#8220;Scientific fluidity&#8221; in translating research into medicine</b>. &nbsp;The authors emphasize that most regulation and review of clinical trials in China continues to occur within an institution, through an institution&#8217;s own Internal Review Board, and absent an external body with review powers, like the U.S. FDA&#8217;s &nbsp;mechanisms. &nbsp;This gives scientists considerably more leeway if the IRBs don&#8217;t function effectively. &nbsp;And effectively function they definitely don&#8217;t. &nbsp;A portion of my seminar paper was on this aspect of the regulation of clinical research; there are definitely serious deficiencies in the composition and functioning of IRBs, at least outside of China&#8217;s major research centers. &nbsp;But as this editorial says, the likelihood that conformance with global standards could occur is pretty high, there&#8217;s a lot of pressure from government officials and scientists alike to institute internationally acceptable standards. &nbsp;The problem, as it always is in China, is implementation.</li>
</ol>
<p>I think the whole article is a pretty fair assessment of the situation three years ago. &nbsp;Certainly, the government has pledged much more funding in the latest Five-Year Plan, but I don&#8217;t know how those funding goals were actually affected by the recession. &nbsp;China&#8217;s talent pool will definitely grow, and we&#8217;ll see whether or not China&#8217;s innovative ability actually increases. &nbsp;That is a development I will be very interested in watching. &nbsp;You hear a lot about the shortcomings of China&#8217;s scientific establishment, and I think the ability or inability of China to create a homegrown industry of innovation will teach the world a lot about what is required to foster creative thinking. &nbsp;And even if China conforms to global standards, the harm to &#8220;scientific fluidity&#8221; might be offset by increased foreign collaboration that such standards would encourage.</p>
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